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Welcome New Members!

  • Posted by ISPE Boston
  • On December 9, 2019
We would like to introduce the Members who joined ISPE in November 2019, welcome them to the Chapter and encourage them (and all of our members) to take advantage of the many professional development, networking and information resources available through ISPE. Fellow ISPE members are a terrific resource for help with everyday professional challenges. And […]
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MDG Hosts Seasonal Celebration and Networking Party

  • Posted by ISPE Boston
  • On December 6, 2019
MDG’s mission is to advance healthcare by enabling diverse professionals to grow through expert forums, collaboration, and knowledge sharing.  In the spirit of our mission and of the holiday season, please join us on December 19th from 5:30 pm to 8:30 pm for our annual Seasonal Celebration and Networking Party, held in honor of our […]
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Thermo Fisher Scientific Opens $90 Million Viral Vector Manufacturing Site in Lexington

  • Posted by ISPE Boston
  • On December 5, 2019
Thermo Fisher Scientific has officially opened its new $90 million viral vector CDMO (contract development and manufacturing organization) site in Lexington. The 50,000-square-foot facility will add more than 200 jobs and support the development, testing and manufacture of viral vectors, which are critical to advancing new life-saving gene and cell therapies globally. Earlier this year, […]
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Novartis Builds Cardiovascular Drug Pipeline with The Medicines Company Acquisition

  • Posted by ISPE Boston
  • On December 5, 2019
Novartis announced today that it has entered into an agreement to acquire The Medicines Company for USD 85.00 per share in cash, valuing the company at approximately USD 9.7 billion on a fully diluted equity basis. The transaction has been unanimously approved by the Boards of Directors of both companies and is expected to close […]
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Karuna’s Schizophrenia Drug Meets Primary Endpoint in Clinical Trial

  • Posted by ISPE Boston
  • On December 5, 2019
Karuna Therapeutics has announced positive results from its Phase 2 clinical trial of KarXT for the treatment of acute psychosis in patients with schizophrenia. “The schizophrenia treatment landscape has remained rather stagnant for decades with therapeutic options relying on discoveries dating back to the 1950s,” said Steve Paul, M.D., chief executive officer, president, and chairman […]
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A Thanksgiving Thank You…

  • Posted by ISPE Boston
  • On November 21, 2019
As the year draws to a close and we look forward to the upcoming holiday fun, we begin to reflect on the many accomplishments (and challenges) of the past year. And with Thanksgiving fast approaching, we also give thought to the many things we are thankful for. Sharing their thoughts are a few of the […]
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Alkermes to Acquire Rodin Therapeutics

  • Posted by ISPE Boston
  • On November 21, 2019
Alkermes is acquiring Rodin Therapeutics, a privately held biopharma focused on synaptopathies. This transaction builds on Alkermes’ experience in central nervous system (CNS) diseases and expands Alkermes’ CNS development efforts into a wide range of neurodegenerative disorders. Synaptic dysfunction is a pathological feature in many neurodegenerative and neuropsychiatric diseases, and synaptic loss correlates closely with […]
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Alnylam Wins FDA Approval for Givlaari

  • Posted by ISPE Boston
  • On November 21, 2019
The FDA has approved Alnylam’s Givlaari (givosiran), an RNAi therapeutic for treatment of adults with acute hepatic porphyria (AHP), a family of ultra-rare, genetic diseases. Long-term complications of AHP can include chronic neuropathic pain, hypertension, chronic kidney disease and liver disease. “AHP can have a profound impact on the lives of patients and their families. […]
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Broad Institute and Novo Ventures Launch Drug Discovery “Greenhouse”

  • Posted by ISPE Boston
  • On November 21, 2019
Novo Ventures and the Broad Institute of MIT and Harvard have announced the launch of the Novo Broad Greenhouse, a joint initiative to discover and propel transformative new therapies from academic science into the clinic. To drive the development of the next generation of molecular medicines, the Novo Broad Greenhouse unites three core ingredients: deep […]
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Combination Gene Therapy Treats Age-Related Diseases in Mice

  • Posted by ISPE Boston
  • On November 13, 2019
A new study from the Wyss Institute at Harvard University and Harvard Medical School (HMS) reports that a single administration of an adeno-associated virus (AAV)-based gene therapy delivering combinations of three longevity-associated genes dramatically improved or completely reversed multiple age-related diseases in mice, suggesting that a systems-level approach to treating such diseases could improve overall […]
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