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ElevateBio Launches with $150M in Series A Financing

  • Posted by ISPE Boston
  • On May 16, 2019
ElevateBio has established ElevateBio BaseCamp, a single R&D, process development and cGMP manufacturing company, to address the process development and manufacturing barriers that can impede the successful development of cell and gene therapies. BaseCamp is providing these and other services across ElevateBio’s portfolio companies and selected strategic partners, enabling them to access state of the […]
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Servier Pharmaceuticals Puts Down Roots in Seaport District

  • Posted by ISPE Boston
  • On May 16, 2019
Servier Pharmaceuticals, a U.S. subsidiary of the global French pharmaceutical company Servier Group, has officially opened its American headquarters in Boston’s new Innovation District. The facility already employs 100 professionals in marketing, business development, R&D and strategic support functions. That figure is projected to double within five years. Servier Group also established the first office […]
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Alnylam and Regeneron to Collaborate on RNAi Therapeutics

  • Posted by ISPE Boston
  • On April 24, 2019
Alnylam and Regeneron have announced a collaboration to discover, develop and commercialize new RNA interference (RNAi) therapeutics with a focus on disease targets expressed in the eye and central nervous system (CNS), in addition to a select number of targets expressed in the liver. The collaboration will leverage both companies’ scientific and technological expertise and […]
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Thermo Fisher to Acquire Brammer Bio

  • Posted by ISPE Boston
  • On April 24, 2019
Thermo Fisher Scientific has announced it will acquire Brammer Bio for approximately $1.7 billion in cash. Brammer Bio is a leading viral vector contract development and manufacturing organization (CDMO) with nearly 600 employees at primary locations in Massachusetts and Florida. Brammer Bio is on track to deliver $250 million of revenue in 2019 and expects to […]
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Ironwood to Focus on GI Diseases, Spins Off Cyclerion Therapeutics

  • Posted by ISPE Boston
  • On April 4, 2019
Ironwood Pharmaceuticals, a GI-focused healthcare company, has announced that it has completed the tax-free spin-off of its soluble guanylate cyclase (sGC) business, Cyclerion Therapeutics. Ironwood is executing on its strategy to drive growth as a GI-focused company, building upon its commercial success with Linzess and advancing its late-stage, first-in-category development candidates including IW-3718 for the […]
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Ironwood Spin-Off Cyclerion Launches as Clinical-Stage Biopharm

  • Posted by ISPE Boston
  • On April 4, 2019
Cyclerion Therapeutics has announced its launch as an independent, publicly traded clinical-stage biopharmaceutical company harnessing the power of soluble guanylate cyclase (sGC) pharmacology to discover, develop and commercialize breakthrough treatments for serious and orphan diseases. Cyclerion will trade on the Nasdaq Global Market, commencing today, under the ticker symbol “CYCN.” “We are excited to unleash […]
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Novartis Adds Anti-Inflammatory Programs with Acquisition of IFM Tre

  • Posted by ISPE Boston
  • On April 3, 2019
Pharmaceutical giant Novartis has announced the planned acquisition of Boston-based start-up IFM Tre, a subsidiary of IFM Therapeutics focused on developing anti-inflammatory medicines targeting the NLRP3 inflammasome. The acquisition will give Novartis full rights to IFM Tre’s portfolio of NLRP3 inhibitors. The NLRP3 (nucleotide-binding domain, leucine-rich repeat-containing receptor pyrin domain containing 3) pathway plays a […]
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Designing Cell Therapy Facilities: Leveraging Operational Simulations

  • Posted by Niranjan Kulkarni, Ph.D
  • On March 26, 2019
Cell therapies are emerging as an important class of next-generation medicines. As many novel treatments move through development to commercialization, manufacturers are challenged to construct optimal facilities for the production of cell therapies. Modeling and simulation at the earliest design stages have many benefits. The number of cell therapy treatments in development has exploded in […]
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Biogen Halts Alzheimer’s Drug Trials

  • Posted by ISPE Boston
  • On March 22, 2019
Biogen and partner Eisai have announced the decision to discontinue the global Phase 3 trials designed to evaluate the efficacy and safety of aducanumab in patients with mild cognitive impairment due to Alzheimer’s disease and mild Alzheimer’s disease dementia. The decision to stop the trials is based on results of a futility analysis conducted by […]
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Pfizer On Track to Acquire Gene Therapy Company

  • Posted by ISPE Boston
  • On March 22, 2019
Pfizer has acquired a 15% equity interest in French biotech Vivet Therapeutics and secured an exclusive option to acquire all outstanding shares. Vivet is a privately company dedicated to developing gene therapy treatments for inherited liver disorders with high unmet medical need. Pfizer and Vivet will collaborate on the development of VTX-801, Vivet’s proprietary treatment […]
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