Vertex Pharmaceuticals has joined forces with California-based Mammoth Biosciences, co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna, to develop in vivo gene-editing therapies for two genetic diseases using Mammoth’s next-generation CRISPR systems. Driven by its unique protein discovery engine, Mammoth’s CRISPR platform consists of a proprietary toolbox of novel, ultracompact Cas enzymes, including Cas14 and […]

Gavi, the Vaccine Alliance has exercised its option to purchase an additional 176.5 million doses of the Moderna COVID-19 vaccine for the COVAX Facility. Of these additional doses, 116.5 million doses are expected to be delivered in the first quarter of 2022 and 60 million doses are expected to be delivered in the second quarter of 2022. […]

Watertown biotech Neumora Therapeutics, a clinical-stage company pioneering precision medicines for brain diseases, has announced its launch. Neumora was founded as a response to the lack of targeted, effective medicines for brain diseases and the high neuroscience drug development failure rate and has raised over $500 million, including a $100 million equity investment from Amgen. […]

The World Health Organization has recommended GSK’s malaria vaccine RTS,S for broader deployment to reduce childhood illness and deaths from malaria in children living in sub-Saharan Africa and other regions with moderate to high transmission. RTS,S is the first and only malaria vaccine to have been shown in pivotal long-term clinical trials to significantly reduce […]